During virion maturation, HIV-1 capsid protein assembles into a conical core containing the viral ribonucleoprotein vRNP complex, thought to be composed mainly of the viral RNA and nucleocapsid protein NC. After infection, the viral RNA is reverse transcribed into double-stranded DNA, which is then incorporated into host chromosomes by integrase IN catalysis. Tomo-bubblegrams also localized NC inside wild-type cores and lining the spherical Gag shell in immature virions.
This article is a stub and is in need of expansion. You can help Villains Wiki by expanding it. Big Bob is a homosexual Guantanamo Bay warden, whose job is to torture the prisoners at Guantanamo Bay Detention Facility as punishment for terrorist attacks upon the United States.
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